Systemic markers of inflammation, endothelial dysfunction, and age-related maculopathy.

  title={Systemic markers of inflammation, endothelial dysfunction, and age-related maculopathy.},
  author={Ronald Klein and Barbara E. Klein and Michael D. Knudtson and Tien Yin Wong and A. Bhavani Shankar and Michael Y Tsai},
  journal={American journal of ophthalmology},
  volume={140 1},
PURPOSE To examine the association of systemic markers of inflammatory disease and endothelial dysfunction with age-related maculopathy (ARM). DESIGN (1) Nested case-control analysis of prevalent ARM and (2) prospective analyses of incident ARM in a random sample of a population-based cohort. METHODS Standardized protocols for blood collection, measurement of markers, administration of a questionnaire, and gradings of stereoscopic color fundus photography to determine ARM were used… CONTINUE READING
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