Systemic manifestations and comorbidities of COPD

@article{Barnes2009SystemicMA,
  title={Systemic manifestations and comorbidities of COPD},
  author={P. Barnes and B. Celli},
  journal={European Respiratory Journal},
  year={2009},
  volume={33},
  pages={1165 - 1185}
}
Increasing evidence indicates that chronic obstructive pulmonary disease (COPD) is a complex disease involving more than airflow obstruction. Airflow obstruction has profound effects on cardiac function and gas exchange with systemic consequences. In addition, as COPD results from inflammation and/or alterations in repair mechanisms, the “spill-over” of inflammatory mediators into the circulation may result in important systemic manifestations of the disease, such as skeletal muscle wasting and… Expand
1,321 Citations

Paper Mentions

Interventional Clinical Trial
Chronic Obstructive Pulmonary Disease (COPD) is a common, preventable and treatable disease that is characterized by persistent respiratory symptoms and airflow limitation that is due… Expand
ConditionsCOPD
InterventionProcedure
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