Systemic lupus erythematosus and human endogenous retroviruses

@article{Sekigawa2003SystemicLE,
  title={Systemic lupus erythematosus and human endogenous retroviruses},
  author={Iwao Sekigawa and Hitoshi Ogasawara and Toshio Naito and Hiroshi Kaneko and Takashi Hishikawa and Hiroshi Hashimoto},
  journal={Modern Rheumatology},
  year={2003},
  volume={13},
  pages={107 - 113}
}
Abstract  Human endogenous retroviruses (HERV) are known to be widely present in the human genome. Several investigations have suggested a possible etiological role of HERV in certain human disorders, including systemic lupus erythematosus (SLE). Here we review and discuss the possible role of HERV, especially HERV clone 4-1, in the onset of SLE, based on recent findings including our own data. 
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