Systemic lupus erythematosus

@article{Manson2006SystemicLE,
  title={Systemic lupus erythematosus},
  author={Jessica Manson and Anisur Rahman},
  journal={Orphanet Journal of Rare Diseases},
  year={2006},
  volume={1},
  pages={6 - 6}
}
Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease, which is autoimmune in origin and is characterized by the presence of autoantibodies directed against nuclear antigens. It is a multi-system disease, and patients can present in vastly different ways. Prevalence varies with ethnicity, but is estimated to be about 1 per 1000 overall with a female to male ratio of 10:1. The clinical heterogeneity of this disease mirrors its complex aetiopathogenesis, which highlights the… 
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