Systemic inflammatory response during cardiopulmonary bypass and strategies.

@article{Li2005SystemicIR,
  title={Systemic inflammatory response during cardiopulmonary bypass and strategies.},
  author={Shu Li and Rick A. Price and Doc Phiroz and Kimberly Swan and Terry A Crane},
  journal={The journal of extra-corporeal technology},
  year={2005},
  volume={37 2},
  pages={180-8}
}
Organ dysfunction after cardiopulmonary bypass (CPB) still is a major problem in patients undergoing cardiovascular surgery. Studies have demonstrated that systemic inflammatory response (SIR) remains one of the major causes of CPB-associated organ injury. The mechanism of SIR during CPB includes the interaction of blood and artificial surface and endotoxemia. The interaction of blood and artificial surface is initiated by protein adsorption. As a result of series of chain reactions, the… CONTINUE READING

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