Systemic inflammation is associated with myocardial fibrosis, diastolic dysfunction, and cardiac hypertrophy in patients with hypertrophic cardiomyopathy.

@article{Fang2017SystemicII,
  title={Systemic inflammation is associated with myocardial fibrosis, diastolic dysfunction, and cardiac hypertrophy in patients with hypertrophic cardiomyopathy.},
  author={L F Fang and Andris Harald Ellims and Anna Louise Beale and Andrew J N Taylor and Andrew J. Murphy and Anthony M Dart},
  journal={American journal of translational research},
  year={2017},
  volume={9 11},
  pages={5063-5073}
}
BACKGROUND Regional or diffuse fibrosis is an early feature of hypertrophic cardiomyopathy (HCM) and is related to poor prognosis. Previous studies have documented low-grade inflammation in HCM. The aim of this study was to examine the relationships between circulating inflammatory markers and myocardial fibrosis, systolic and diastolic dysfunction, and the degree of cardiac hypertrophy in HCM patients. METHODS AND RESULTS Fifty HCM patients were recruited while 20 healthy subjects served as… CONTINUE READING

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