Systemic hypoxia promotes lymphocyte apoptosis induced by oxidative stress during moderate exercise

@article{Wang2009SystemicHP,
  title={Systemic hypoxia promotes lymphocyte apoptosis induced by oxidative stress during moderate exercise},
  author={Jong-Shyan Wang and Chia-Te Lin},
  journal={European Journal of Applied Physiology},
  year={2009},
  volume={108},
  pages={371-382}
}
Blood undergoes oxidative stress during severe hypoxia or intense exercise. Excessive exposure to oxidative stress induces replicative senescence and apoptosis of lymphocytes. This study determines how various exercises with/without hypoxia affect lymphocyte subset mobilization and oxidative stress-induced lymphocyte apoptosis. Eighteen sedentary males randomly engaged in two normoxic exercise bouts [severe exercise (SE) (up to VO2max) and moderate-intensity exercise (ME) (50%VO2max) while… CONTINUE READING