Systemic hypertension at 4,300 m is related to sympathoadrenal activity.

  title={Systemic hypertension at 4,300 m is related to sympathoadrenal activity.},
  author={Eugene E Wolfel and M. A. Selland and Robert S. Mazzeo and John R T Reeves},
  journal={Journal of applied physiology},
  volume={76 4},
Residence at high altitude has been associated with elevation in systemic arterial blood pressure, but the time course has been little studied and the mechanism is unknown. Because plasma epinephrine (E) and norepinephrine (NE) also increase at altitude, we hypothesized that heightened sympathoadrenal activity may cause increased arterial pressure. We measured ambulatory blood pressure by cuff monitor in relation to 24-h urinary excretion of E and NE at sea level and during 3 wk of residence at… CONTINUE READING

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