Systemic effects of periodontal disease in cats

  title={Systemic effects of periodontal disease in cats},
  author={NJ Cave and J P Bridges and David G. Thomas},
  journal={Veterinary Quarterly},
  pages={131 - 144}
Background: Periodontal disease in cats is a local disease that may have systemic consequences that are affected by treatment. Objective: To test the hypotheses that systemic health indices would be correlated with the severity of periodontitis, and would improve with treatment. Animals and methods: Apparently otherwise healthy cats from an in-bred colony were randomly assigned to a treatment group (n = 30), or a control group (n = 18), which was left untreated for 3 months. Periodontal disease… 
Periodontal disease in cats
Treatment for periodontitis in cats aims to control tissue inflammation, returning the gingiva to clinical health and preventing destruction of the periodontium in other parts of the mouth.
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A comprehensive overview of mucosal vaccination strategies to induce protective immunity in the oral cavity for periodontal disease control is offered and the need for additional research with appropriate and clinically relevant animal models is highlighted.
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Experimental animal models of periodontitis have provided mostly consistent data on systemic inflammatory host response, but the data from the clinical studies are more variable, especially when obtained from patients post treatment.
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  • Medicine, Biology
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Tissue engineering has been proven to successfully regenerate lost periodontal tissues and this new possibility for treating veterinary patients is discussed, including scaffolds, signaling molecules, stem cells, and gene therapy.
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A significant relationship between periodontal disease, regardless of its intensity, and blood lipid levels in the studied population confirms that periodontitis may be a risk factor and may contribute to the pathogenesis of atherosclerosis and cardiovascular diseases (CVD).
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It can be concluded that, like any other chronic condition, chronic periodontitis can lead to anemia, and the correlation between signs of anemia and chronicperiodontitis is determined.
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