Systemic dissemination by intrarectal infection with Listeria monocytogenes in mice.

@article{Nishikawa1998SystemicDB,
  title={Systemic dissemination by intrarectal infection with Listeria monocytogenes in mice.},
  author={Shohei Nishikawa and M Hirasue and Tomisato Miura and Kyogo Yamada and Sanae Sasaki and Akio Nakane},
  journal={Microbiology and immunology},
  year={1998},
  volume={42 4},
  pages={325-7}
}
Orally ingested Listeria monocytogenes is known to penetrate into Peyer's patches (PP) and translocate to the spleen and liver. Herein, extraintestinal dissemination of the bacterium independent of PP was investigated. Dissemination of Listeriae to the spleen and liver was observed in intrarectally infected mice as well as in intragastrically infected animals in spite that no Listeriae were detected in the small intestines of mice infected intrarectally. Decreased numbers of intestinal… CONTINUE READING

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