Systemic delivery of human microdystrophin to regenerating mouse dystrophic muscle by muscle progenitor cells.

Abstract

Cell-based therapy for Duchenne muscular dystrophy patients and mdx mice has proven to be a safe but ineffective form of treatment. Recently, a group of cells called muscle side population (SP) cells have been isolated based on their ability to efflux the DNA-binding dye Hoechst. To understand the potential of skeletal muscle SP cells to serve as precursors… (More)

5 Figures and Tables

Topics

  • Presentations referencing similar topics