Systemic cytokine profiles and splenic toll-like receptor expression during Trichinella spiralis infection.

@article{Yu2013SystemicCP,
  title={Systemic cytokine profiles and splenic toll-like receptor expression during Trichinella spiralis infection.},
  author={Y Yu and Ming-Jun Deng and Wei-wei Lu and Mo-Zhi Jia and Wei Wu and Yong-fen Qi},
  journal={Experimental parasitology},
  year={2013},
  volume={134 1},
  pages={92-101}
}
Parasitic helminth and their products can suppress or modulate the host immune response for long-term survival and continued infection. Commonly, helminth can induce conditional T helper cell type 2 (Th2) response, regulatory T cell and cytokines, and altered function of antigen presentation cells by modulating toll-like receptors (TLRs). The helminth Trichinella spiralis establishes chronic infection in skeletal muscles of a wide range of mammalian hosts. We infected mice with T. spiralis and… CONTINUE READING

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