Systemic cyclosporine in high-risk keratoplasty: Long-term results

@article{Hill1995SystemicCI,
  title={Systemic cyclosporine in high-risk keratoplasty: Long-term results},
  author={John C Hill},
  journal={Eye},
  year={1995},
  volume={9},
  pages={422-428}
}
Systemic cyclosporine (CSA) was given to 43 high-risk keratoplasty patients (vascularisation in three or four quadrants and >16 stromal vessels): 14 received CSA for 12 months (long CSA group) and 29 for a 4-6 month period (short CSA group). A group of 37 similar high-risk keratoplasty patients received no CSA (no CSA group). In the no CSA group 27 (73%) grafts had rejection episodes compared with 21 (48.8%) in the combined CSA group (p = 0.025). Rejection was reversed in only 23.3% of the no… CONTINUE READING