Systemic complement depletion inhibits experimental cerebral vasospasm.

@article{German1996SystemicCD,
  title={Systemic complement depletion inhibits experimental cerebral vasospasm.},
  author={John W. German and Cordell E. Gross and Patricia C. Giclas and W Watral and Martin Bednar},
  journal={Neurosurgery},
  year={1996},
  volume={39 1},
  pages={
          141-5; discussion 145-6
        }
}
OBJECTIVE Cerebral vasospasm is the leading cause of morbidity and mortality in patients who are hospitalized because of aneurysmal subarachnoid hemorrhage (SAH). Recent work has suggested that activation of the complement cascade contributes to the development of cerebral vasospasm. To further examine this hypothesis, a rabbit model of SAH was employed. METHODS Two milliliters of autologous arterial blood was injected into the region of the perimesencephalic cistern. Forty-eight hours after… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 20 CITATIONS

Similar Papers

Loading similar papers…