Systemic cobalt toxicity from total hip arthroplasties: review of a rare condition Part 1 - history, mechanism, measurements, and pathophysiology.

@article{Cheung2016SystemicCT,
  title={Systemic cobalt toxicity from total hip arthroplasties: review of a rare condition Part 1 - history, mechanism, measurements, and pathophysiology.},
  author={Annie Cheung and Samik Banerjee and Jeffery J Cherian and Florence Wong and Jagdish W Butany and Cameron J Gilbert and Chris Overgaard and Khalid A. Syed and Michael G. Zywiel and Joshua.J. Jacobs and M. Mont},
  journal={The bone & joint journal},
  year={2016},
  volume={98-B 1},
  pages={6-13}
}
UNLABELLED Recently, the use of metal-on-metal articulations in total hip arthroplasty (THA) has led to an increase in adverse events owing to local soft-tissue reactions from metal ions and wear debris. While the majority of these implants perform well, it has been increasingly recognised that a small proportion of patients may develop complications secondary to systemic cobalt toxicity when these implants fail. However, distinguishing true toxicity from benign elevations in cobalt ion levels… CONTINUE READING
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