Systemic ciclosporin A in high-risk keratoplasties

  title={Systemic ciclosporin A in high-risk keratoplasties},
  author={Thomas Reinhard and Rainer Sundmacher and Peter Julius Heering},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
• Background: It was the purpose of this study to compile the results of all high-risk keratoplasties (kp) performed in our hospital under systemic ciclosporin A (Ci A) cover from 1987 through 1994. • Methods: One hundred and thirty-one keratoplasties were performed. Ci A was administered for an average period of 9.4 months. We aimed at trough levels of 100–150 ng/ml (monoclonal RIA/TDx). The 29 kp in group A were second or third repeat kp and/or the recipient cornea had severe deep… CONTINUE READING


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