Systemic chemotherapy for gastric carcinoma followed by postoperative intraperitoneal therapy: a final report.

@article{Crookes1997SystemicCF,
  title={Systemic chemotherapy for gastric carcinoma followed by postoperative intraperitoneal therapy: a final report.},
  author={Peter F. Crookes and Cynthia Gail Leichman and Lawrence Leichman and Ming Jun Andrew Tan and Loren Laine and Steve Stain and Joaquina Celebre Baranda and Y Casagrande and Susan Groshen and Howard Silberman},
  journal={Cancer},
  year={1997},
  volume={79 9},
  pages={1767-75}
}
BACKGROUND Because only approximately 50% of gastric carcinomas are resectable for cure, the authors hypothesized that effective systemic preoperative (neoadjuvant) chemotherapy, aimed at decreasing the size and extent of the primary tumor and eradicating distant microscopic disease, may increase the rate of resectability and have a greater impact on survival than postoperative (adjuvant) treatment alone. In addition, because the peritoneal cavity is the most common site of first recurrence… CONTINUE READING

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