Systemic antimicrobials adjunctive to a repeated mechanical and antiseptic therapy for aggressive periodontitis: a 6-month randomized controlled trial.

@article{Varela2011SystemicAA,
  title={Systemic antimicrobials adjunctive to a repeated mechanical and antiseptic therapy for aggressive periodontitis: a 6-month randomized controlled trial.},
  author={Victor Macedo Varela and D{\'e}bora Heller and Mayra Xavier e Silva-Senem and Maria Cyn{\'e}sia Medeiros de Barros Torres and Ana Paula Vieira Colombo and Eduardo Jorge Feres-Filho},
  journal={Journal of periodontology},
  year={2011},
  volume={82 8},
  pages={1121-30}
}
BACKGROUND The purpose of this study is to compare the additional benefit of systemic antimicrobials versus placebos to a repeated mechanical instrumentation combined with comprehensive local chemical plaque control for the periodontal treatment of generalized aggressive periodontitis (GAgP). METHODS This was a 6-month randomized, double-masked, placebo-controlled clinical trial. All GAgP patients received full-mouth disinfection followed by staged scaling and root planing without (placebo… CONTINUE READING
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