Systemic anticoagulant effect of low-dose subcutaneous unfractionated heparin as determined using thrombelastography.

@article{Matzelle2007SystemicAE,
  title={Systemic anticoagulant effect of low-dose subcutaneous unfractionated heparin as determined using thrombelastography.},
  author={Shannon J. Matzelle and Neville M. Gibbs and William M. Weightman and Matthew R. Sheminant and Ronda Rowe and Stuart P. Baker},
  journal={Anaesthesia and intensive care},
  year={2007},
  volume={35 4},
  pages={
          498-504
        }
}
In an observational study using heparinase-modified thrombelastography, we investigated the percentage of elective cardiothoracic surgical patients receiving low-dose unfractionated heparin (5000 IU 12 hourly subcutaneously) who had a demonstrable systemic heparin effect. Blood samples were obtained at induction from 40 adult elective cardiothoracic surgical patients who had received 5000 IU unfractionated heparin subcutaneously within six hours. Simultaneous kaolin and heparinase-modified… CONTINUE READING
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