Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis.

Abstract

Although(,) vascular remodeling is a hallmark of many chronic inflammatory disorders such as rheumatoid arthritis, inflammatory bowel disease, and psoriasis, anti-vascular strategies to treat these conditions have received little attention to date. We investigated the anti-inflammatory activity of systemic blockade of VEGF-A by the inhibitory monoclonal… (More)
DOI: 10.1073/pnas.0907550106

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@article{Schonthaler2009SystemicAT, title={Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis.}, author={Helia Berrit Schonthaler and Reto Huggenberger and Stefanie K. Wculek and Michael Detmar and Erwin F Wagner}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2009}, volume={106 50}, pages={21264-9} }