Systemic and topical antibiotics for chronic rhinosinusitis.

@article{Head2016SystemicAT,
  title={Systemic and topical antibiotics for chronic rhinosinusitis.},
  author={Karen Head and Lee Yee Chong and Patorn Piromchai and Claire Hopkins and Carl M. Philpott and Anne G M Schilder and Martin J. Burton},
  journal={The Cochrane database of systematic reviews},
  year={2016},
  volume={4},
  pages={
          CD011994
        }
}
BACKGROUND This review is one of six looking at the primary medical management options for patients with chronic rhinosinusitis.Chronic rhinosinusitis is common and is characterised by inflammation of the lining of the nose and paranasal sinuses leading to nasal blockage, nasal discharge, facial pressure/pain and loss of sense of smell. The condition can occur with or without nasal polyps. Systemic and topical antibiotics are used with the aim of eliminating infection in the short term (and… 

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Different types of intranasal steroids for chronic rhinosinusitis.

Low quality evidence was found relating to disease severity and nasal polyps size, with results from the high-dose and low-dose groups being similar and the primary adverse effect, epistaxis, was more common when higher doses were used.

Short-course oral steroids alone for chronic rhinosinusitis.

The results at the end of treatment showed an improvement in patients receiving oral steroids compared to placebo, both when presented as a mean final value and as a change from baseline, which corresponds to a large effect size.

Saline irrigation for chronic rhinosinusitis.

The effects of saline irrigation in patients with chronic rhinosinusitis was evaluated and the evidence was assessed to be of low quality for the three months follow-up and very lowquality for the six months following-up.

Intranasal steroids versus placebo or no intervention for chronic rhinosinusitis.

The effects of intranasal corticosteroids in people with chronic rhinosinusitis were assessed, disease-specific health-related quality of life (HRQL), patient-reported disease severity and the commonest adverse event - epistaxis.

Short-course oral steroids as an adjunct therapy for chronic rhinosinusitis.

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