Systemic and mucosal immunization with Candida albicans hsp90 elicits hsp90-specific humoral response in vaginal mucosa which is further enhanced during experimental vaginal candidiasis.

@article{Raka2008SystemicAM,
  title={Systemic and mucosal immunization with Candida albicans hsp90 elicits hsp90-specific humoral response in vaginal mucosa which is further enhanced during experimental vaginal candidiasis.},
  author={Milan Ra{\vs}ka and Jana Běl{\'a}kov{\'a} and Milada Stuchlov{\'a} Horynov{\'a} and Michal Křupka and Jiř{\'i} Novotn{\'y} and Martina Sebestov{\'a} and Ev{\vz}en Weigl},
  journal={Medical mycology},
  year={2008},
  volume={46 5},
  pages={411-20}
}
The Candida albicans heat shock protein 90 kDa (hsp90-CA) is an important target for protective antibodies in disseminated candidiasis of experimental mice and humans. Hsp90-CA is present in the cell wall of Candida pseudohyphae or hyphae--typical pathogenic morphotypes in both mucosal and systemic Candida infections. However, the potential protective… CONTINUE READING