Systemic administration of lentinan, a branched beta-glucan, enhances long-term potentiation in the rat dentate gyrus in vivo.

@article{Edagawa2001SystemicAO,
  title={Systemic administration of lentinan, a branched beta-glucan, enhances long-term potentiation in the rat dentate gyrus in vivo.},
  author={Yoshikuni Edagawa and Miroslav Smriga and Nobuyoshi Nishiyama and Hiroshi Saito},
  journal={Neuroscience letters},
  year={2001},
  volume={314 3},
  pages={139-42}
}
We investigated the effects of oral and intravenous application of lentinan, a branched beta-glucan, on the induction of long-term potentiation (LTP) in the rat dentate gyrus in vivo. Oral administration of lentinan (200 mg/kg) enhanced the induction of LTP evoked by sub-threshold tetanic stimulation (20 pulses at 60 Hz) of the perforant pathway without… CONTINUE READING