Systemic administration of l-kynurenine sulfate induces cerebral hypoperfusion transients in adult C57Bl/6 mice.

Abstract

The kynurenine pathway is a cascade of enzymatic steps generating biologically active compounds. l-kynurenine (l-KYN) is a central metabolite of tryptophan degradation. In the mammalian brain, l-KYN is partly converted to kynurenic acid (KYNA), which exerts multiple effects on neurotransmission. Recently, l-KYN or one of its derivatives were attributed a… (More)
DOI: 10.1016/j.mvr.2017.05.006

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Cite this paper

@article{Varga2017SystemicAO, title={Systemic administration of l-kynurenine sulfate induces cerebral hypoperfusion transients in adult C57Bl/6 mice.}, author={D{\'a}niel Varga and {\'A}kos Menyh{\'a}rt and Tam{\'a}s Pusk{\'a}s and Ferenc Bari and Eszter Farkas and Zsolt Kis and L{\'a}szl{\'o} V{\'e}csei and J{\'o}zsef Toldi and Levente Gell{\'e}rt}, journal={Microvascular research}, year={2017}, volume={114}, pages={19-25} }