Systemic administration of baclofen and the GABAB antagonist, CGP 35348, does not affect GABA, glutamate or aspartate in microdialysates of the striatum of conscious rats

Abstract

Previous in vitro experiments have shown that the GABAB agonist, baclofen, and the antagonist, CGP 35348, respectively, decrease and increase the autoreceptor-mediated release of GABA in brain slices and synaptosomes. Since it is not clear whether these autoreceptors are operative in vivo, an attempt was made to reproduce these results in brain dialysis… (More)
DOI: 10.1007/BF00168947

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@article{Waldmeier1992SystemicAO, title={Systemic administration of baclofen and the GABAB antagonist, CGP 35348, does not affect GABA, glutamate or aspartate in microdialysates of the striatum of conscious rats}, author={Peter C. Waldmeier and Kurt St{\"{o}cklin and J. -J. Feldtrauer}, journal={Naunyn-Schmiedeberg's Archives of Pharmacology}, year={1992}, volume={345}, pages={548-552} }