Systemic Treatment in Severe Cases of Recurrent Aphthous Stomatitis: An Open Trial

@article{Mimura2009SystemicTI,
  title={Systemic Treatment in Severe Cases of Recurrent Aphthous Stomatitis: An Open Trial},
  author={Maria Angela Martins Mimura and S{\'i}lvio Kenji Hirota and Norberto Sugaya and J. A. L. Sanches and Dante Migliari},
  journal={Clinics (Sao Paulo, Brazil)},
  year={2009},
  volume={64},
  pages={193 - 198}
}
PURPOSE This study aimed to evaluate the efficacy of the systemic drugs thalidomide, dapsone, colchicine, and pentoxifylline in the treatment of severe manifestations of RAS. METHODS An open, 4-year clinical trial was carried out for 21 consecutive patients with severe RAS. Initially, patients were given a 2-week course of prednisone to bring them to a baseline status. Simultaneously, one of the four test drugs was assigned to each patient to be taken for a period of 6 months. During the… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 32 references

Recurrent aphthous ulcers today: a review of the growing knowledge.

International journal of oral and maxillofacial surgery • 2004
View 8 Excerpts
Highly Influenced

Crossover study of thalidomide vs placebo in severe recurrent aphthous stomatitis.

Archives of dermatology • 1990
View 5 Excerpts
Highly Influenced

Treatment of aphthae with thalidomide.

Journal of the American Academy of Dermatology • 1989
View 4 Excerpts
Highly Influenced

Oxypentifylline in the management of recurrent aphthous oral ulcers: an open clinical trial.

Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics • 1999
View 4 Excerpts
Highly Influenced

Recurrent aphthous stomatitis.

Dental clinics of North America • 2005
View 3 Excerpts

The effects of colchicine on neutrophil function in subjects with recurrent aphthous stomatitis.

Journal of the European Academy of Dermatology and Venereology : JEADV • 2003
View 1 Excerpt

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