Systemic Toxicity and Cardiotoxicity From Local Anesthetics: Incidence and Preventive Measures

@article{Mulroy2002SystemicTA,
  title={Systemic Toxicity and Cardiotoxicity From Local Anesthetics: Incidence and Preventive Measures},
  author={M. Mulroy},
  journal={Regional Anesthesia & Pain Medicine},
  year={2002},
  volume={27},
  pages={556 - 561}
}
  • M. Mulroy
  • Published 2002
  • Medicine
  • Regional Anesthesia & Pain Medicine
Central nervous system toxicity from unintentionally high blood levels has been a significant concern and risk with local anesthetics since their discovery. Cardiotoxicity associated with toxic blood levels of long-acting local anesthetics1 has heightened concern about systemic blood levels in the last 20 years. This review will discuss the apparent incidence of systemic toxicity, the situations in which it occurs, some of the other risks of regional anesthesia, and appropriate safety steps to… Expand
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