Systemic Therapy for Hepatocellular Carcinoma: Cytotoxic Chemotherapy, Targeted Therapy and Immunotherapy

Abstract

Conventional cytotoxic chemotherapy has not provided clinical benefit or prolonged survival for patients with advanced HCC. This review summarizes the results of prospective clinical trials of several categories of systemic therapy, with emphasis on the more promising results from recent trials of biologically targeted therapeutic agents in HCC.

DOI: 10.1245/s10434-007-9705-0

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@article{Thomas2007SystemicTF, title={Systemic Therapy for Hepatocellular Carcinoma: Cytotoxic Chemotherapy, Targeted Therapy and Immunotherapy}, author={Melanie Byrne Thomas and James P. O’Beirne and Junji Furuse and Anthony T. C. Chan and Ghassan Khaled Abou-Alfa and Philip J M Johnson}, journal={Annals of Surgical Oncology}, year={2007}, volume={15}, pages={1008-1014} }