Systemic Lupus Erythematosus Patients with Central Nervous System Involvement Show Autoantibodies to a 50-kD Neuronal Membrane Protein By Veneta


An antibody was detected in the sera from patients with systemic lupus erythematosus (SLE) and central nervous system (CNS) involvement that reacted with a 50-kD antigen in the plasma membrane of brain synaptic terminals. The 50-kD antigen was solubilized with Triton X-100 from preparations enriched with synaptic plasma membranes, and was partially purified… (More)


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