Systemic Amyloidosis Recognition, Prognosis, and Therapy: A Systematic Review.

@article{Gertz2020SystemicAR,
  title={Systemic Amyloidosis Recognition, Prognosis, and Therapy: A Systematic Review.},
  author={Morie A. Gertz and Angela Dispenzieri},
  journal={JAMA},
  year={2020},
  volume={324 1},
  pages={
          79-89
        }
}
Importance Many patients with systemic amyloidosis are underdiagnosed. Overall, 25% of patients with immunoglobulin light chain (AL) amyloidosis die within 6 months of diagnosis and 25% of patients with amyloid transthyretin (ATTR) amyloidosis die within 24 months of diagnosis. Effective therapy exists but is ineffective if end-organ damage is severe. Objective To provide evidence-based recommendations that could allow clinicians to diagnose this rare set of diseases earlier and enable… 
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