Systemic Activation of Activin A Signaling Causes Chronic Kidney Disease-Mineral Bone Disorder

@inproceedings{Sugatani2018SystemicAO,
  title={Systemic Activation of Activin A Signaling Causes Chronic Kidney Disease-Mineral Bone Disorder},
  author={Toshifumi Sugatani},
  booktitle={International journal of molecular sciences},
  year={2018}
}
The high cardiovascular mortality associated with chronic kidney disease (CKD) is caused in part by the CKD-mineral bone disorder (CKD-MBD) syndrome. The CKD-MBD consists of skeletal, vascular and cardiac pathology caused by metabolic derangements produced by kidney disease. The prevalence of osteopenia/osteoporosis resulting from the skeletal component of the CKD-MBD, renal osteodystrophy (ROD), in patients with CKD exceeds that of the general population and is a major public health concern… CONTINUE READING
4
Twitter Mentions

References

Publications referenced by this paper.
SHOWING 1-10 OF 147 REFERENCES

Building strong bones: molecular regulation of the osteoblast lineage

  • Nature Reviews Molecular Cell Biology
  • 2011
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Mechanisms involved in enhancement of osteoclast formation by activin-A.

  • Journal of cellular biochemistry
  • 2018
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Genomewide comprehensive analysis reveals critical cooperation between Smad and c-Fos in RANKL-induced osteoclastogenesis.

  • Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
  • 2015
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…