Systematic search of susceptibility loci with methods using gametic disequilibrium.

Abstract

Susceptibility genes are identified for a simulated complex trait by a systematic genome search for linkage between disease and a genetic marker in the presence of gametic disequilibrium. The transmission/disequilibrium tests TDTa or TDTg for multiallelic markers compare transmitted and nontransmitted alleles or the genotypes formed by the two transmitted… (More)

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@article{Bickebller1995SystematicSO, title={Systematic search of susceptibility loci with methods using gametic disequilibrium.}, author={Heike Bickeb{\"{o}ller and Patricia Margaritte-Jeannin and M C Babron and F. Clerget-Darpoux}, journal={Genetic epidemiology}, year={1995}, volume={12 6}, pages={577-82} }