Systematic screening of the LDL-PLA2 gene for polymorphic variants and case-control analysis in schizophrenia.

@article{Bell1997SystematicSO,
  title={Systematic screening of the LDL-PLA2 gene for polymorphic variants and case-control analysis in schizophrenia.},
  author={Rachel E. Bell and David A. Collier and Simon Q Rice and Gareth W Roberts and Colin H. Macphee and Robert W. Kerwin and Janis Price and Israel S. Gloger},
  journal={Biochemical and biophysical research communications},
  year={1997},
  volume={241 3},
  pages={630-5}
}
Systematic scans of the genome using microsatellite markers have identified chromosome 6p21.1 as a putative locus for schizophrenia in multiply affected families. There is also evidence from a series of studies for a role of abnormal phospholipid metabolism in schizophrenia. In light of these findings, and the role of platelet activating factor in neurotransmission and neurodevelopment, we have examined the LDL-PLA2 (plasma PAF acetylhydrolase, PAF-AH) gene, a serine dependent phospholipase… CONTINUE READING

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Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia, part III: Molecular mechanisms.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry • 2017
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