Systematic reviews and meta-analyses of randomized trials: principles and pitfalls.

@article{Costa2014SystematicRA,
  title={Systematic reviews and meta-analyses of randomized trials: principles and pitfalls.},
  author={Bruno R. da Costa and Peter Jűni},
  journal={European heart journal},
  year={2014},
  volume={35 47},
  pages={
          3336-45
        }
}
Systematic reviews and meta-analyses allow for a more transparent and objective appraisal of the evidence. They may decrease the number of false-negative results and prevent delays in the introduction of effective interventions into clinical practice. However, as for any other tool, their misuse can result in severely misleading results. In this article,we discuss the main steps that should be taken when conducting systematic reviews and meta-analyses, namely the preparation of a review… CONTINUE READING

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