Systematic review with network meta-analysis: the efficacy of anti-tumour necrosis factor-alpha agents for the treatment of ulcerative colitis.

@article{Stidham2014SystematicRW,
  title={Systematic review with network meta-analysis: the efficacy of anti-tumour necrosis factor-alpha agents for the treatment of ulcerative colitis.},
  author={R W Stidham and Tae Hwa Lee and Peter D. R. Higgins and Amar R. Deshpande and Daniel Sussman and Amit G. Singal and B Joseph Elmunzer and Sameer D. Saini and Sandeep Vijan and Akbar K Waljee},
  journal={Alimentary pharmacology & therapeutics},
  year={2014},
  volume={39 7},
  pages={660-71}
}
BACKGROUND Antibodies against tumour necrosis factor-alpha (anti-TNF) are effective therapies in the treatment of ulcerative colitis (UC), but their comparative efficacy is unknown. AIM To perform a network meta-analysis comparing the efficacy of anti-TNF agents in UC. METHODS After screening 506 studies, reviewers extracted information on seven studies. Traditional meta-analysis (TMA) was used to compare each anti-TNF agent to placebo. Bayesian network meta-analysis (NMA) was performed to… CONTINUE READING
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