Systematic review with meta-analysis: mucosal healing is associated with improved long-term outcomes in Crohn's disease.

@article{Shah2016SystematicRW,
  title={Systematic review with meta-analysis: mucosal healing is associated with improved long-term outcomes in Crohn's disease.},
  author={Shailja C. Shah and J. F. Colombel and Bruce E Sands and Neeraj Narula},
  journal={Alimentary pharmacology & therapeutics},
  year={2016},
  volume={43 3},
  pages={317-33}
}
BACKGROUND Clinical manifestations of Crohn's disease (CD) do not reliably correlate with endoscopic activity. While treating to achieve clinical remission (CR) has neither proven to improve CD outcomes nor alter the natural disease course, it is unclear whether targeting objective measures like mucosal healing (MH) is associated with improved long-term outcomes. AIM To perform a systematic review and meta-analysis comparing long-term outcomes in active CD patients who achieve MH compared to… CONTINUE READING