Systematic review with meta‐analysis: the efficacy and safety of tenofovir to prevent mother‐to‐child transmission of hepatitis B virus

@article{Hyun2017SystematicRW,
  title={Systematic review with meta‐analysis: the efficacy and safety of tenofovir to prevent mother‐to‐child transmission of hepatitis B virus},
  author={Myung Han Hyun and Y-S Lee and J H Kim and Ji Hye Je and Yang Jae Yoo and Jong Eun Yeon and Kwan Soo Byun},
  journal={Alimentary Pharmacology \& Therapeutics},
  year={2017},
  volume={45},
  pages={1493 - 1505}
}
  • M. Hyun, Y-S Lee, K. Byun
  • Published 1 June 2017
  • Medicine, Biology
  • Alimentary Pharmacology & Therapeutics
Preventing mother to child transmission of chronic hepatitis B infection in the setting of a high maternal viral load is challenging. The idea has emerged from antepartum tenofovir treatment with combination immunoprophylaxis. 
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The benefits of different antiviral regimens in pregnant women with hepatitis B virus (HBV) infection are explored in an attempt to provide scientific reference for clinically relevant interventions.
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In pregnant women who have high HBV DNA titers, TDF can reduce the perinatal transmission from mother to child without significant adverse events.
Letter: role of tenofovir to prevent mother‐to‐child transmission of hepatitis B virus—authors’ reply
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A phase III, placebocontrolled, double-blind, randomized clinical trial to assess the efficacy and safety of a short course of tenofovir disoproxil fumarate in women with hepatitis B virus e-antigen.
Identifying gaps across the cascade of care for the prevention of HBV mother‐to‐child transmission in Burkina Faso: Findings from the real world
TLDR
This pilot study aimed to describe the cascade of care for hepatitis B PMTCT in a real life situation, and to identify sociodemographic factors associated with adequate management of pregnant women and infants.
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