Systematic review with meta‐analysis: Saccharomyces boulardii supplementation and eradication of Helicobacter pylori infection

  title={Systematic review with meta‐analysis: Saccharomyces boulardii supplementation and eradication of Helicobacter pylori infection},
  author={Hania Szajewska and Andrea Horv{\'a}th and Maciej Kołodziej},
  journal={Alimentary Pharmacology \& Therapeutics},
Unsatisfactory Helicobacter pylori eradication rates and therapy‐associated side effects remain a problem. 
Saccharomyces boulardii as an adjuvant therapy for Helicobacter pylori eradication: A systematic review and meta‐analysis with trial sequential analysis
The aim of the study was to update and determine the effects of S boulardii as an adjuvant therapy on H pylori eradication rates and adverse effects.
Systematic review with meta‐analysis: Lactobacillus rhamnosus GG in the prevention of antibiotic‐associated diarrhoea in children and adults
The effects of probiotics are strain specific. The clinical effects of each strain need to be evaluated separately.
Saccharomyces boulardii as therapeutic alternative in experimental giardiasis
The objective of this study was to evaluate the effect of treatment with the probiotic Saccharomyces boulardii with or without metronidazole in experimental giardiasis.
Strategies for Helicobacter pylori eradication in the year 2020
To highlight the concerns caused by the increasing resistance of H. pylori to antibiotics, in particular to clarithromycin, the World Health Organization added this microorganism in the priority list for research and development of new antibiotics.
Saccharomyces boulardii Combined With Quadruple Therapy for Helicobacter pylori Eradication Decreased the Duration and Severity of Diarrhea: A Multi-Center Prospective Randomized Controlled Trial
The joint use of S. boulardii and quadruple therapy markedly improved the overall pre-eradication alimentary symptoms and ameliorated H. pylori eradication-induced antibiotic-associated side effects.
[Underwater rocks of anti - helicobacter therapy].
The most significant factors influencing the effective implementation of modern anti-Helicobacter therapy regimens should be adherence of physicians to the use of clinical guidelines, patient adherence to prescriptions and recommendations of specialists, as well as adherence to eradication treatment protocols.
How can Helicobacter pylori eradication therapies be improved ?
This poster presents a probabilistic procedure that can be used as a guide to select patients suitable for surgery for Gastroenterology at the National University of Colombia with a history of organ failure.
Probiotic monotherapy and Helicobacter pylori eradication: A systematic review with pooled-data analysis
Probiotics alone show a minimal effect on H. pylori clearance, thus suggesting a likely direct role, and no significant difference in adverse events was found between probiotics and placebo.
Treatment of Helicobacter pylori infection 2016
This article will address the published literature over the last year pertaining to the topic of treatment of H. pylori infection, assessing the efficacy of standard triple therapy, as well as exploring new first‐line treatments, mainly optimized nonbismuth‐containing and bismuth-containing quadruple therapies with some promising data also emerging on dual therapy.
Saccharomyces boulardii CNCM I-745 plus sequential therapy for Helicobacter pylori infections: a randomized, open-label trial
Addition of S. boulardii to sequential therapy improved H. pylori eradication rate and reduced the incidence of treatment-associated AEs in Moroccan patients with H.pylori infection.


Meta‐analysis: the effects of Saccharomyces boulardii supplementation on Helicobacter pylori eradication rates and side effects during treatment
Aliment Pharmacol Ther 2010; 32: 1069–1079
A randomized, open trial evaluating the effect of Saccharomyces boulardii on the eradication rate of Helicobacter pylori infection in children
The failure rate of Helicobacter pylori eradication imposes the assessment of new options in eradication and this results in the development of new strategies for eradication of the bug.
Meta‐analysis: non‐pathogenic yeast Saccharomyces boulardii in the prevention of antibiotic‐associated diarrhoea
This work has shown that probiotic‐associated diarrhoea occurs in up to 30% of patients who receive antibiotics but can be prevented with probiotics, and this should not be considered a cause for concern.
Optimised empiric triple and concomitant therapy for Helicobacter pylori eradication in clinical practice: the OPTRICON study
Empiric triple therapy for Helicobacter pylori should be abandoned when clarithromycin resistance rate is >15–20%, and optimisation of triple therapy can increase eradication rates by 10%.
The Effect of Probiotics and Mucoprotective Agents on PPI‐Based Triple Therapy for Eradication of Helicobacter pylori
This work evaluated the additive effects of Saccharomyces boulardii combined with proton pump inhibitor (PPI)‐based triple therapy and a mucoprotective agent coupled with PPI‐ based triple therapy for HP eradication.
Efficacy and Safety of Saccharomyces boulardii in the 14‐day Triple Anti‐Helicobacter pylori Therapy: A Prospective Randomized Placebo‐Controlled Double‐Blind Study
The aim of the study was to investigate the efficacy and safety of S. boulardii in the prevention of side‐effects related to H. pylori eradication and to define the effect ofS.
Intervention study on Saccharomyces boulardii with proton pump inhibitor (PPI)-based triple therapy for Helicobacter pylori related peptic ulcer
S. boulardii with PPI-based triple therapy for peptic ulcer is effective with a low recurrence rate and can reduce the incidence of adverse events.
Meta-analysis of the efficacy of probiotics in Helicobacter pylori eradication therapy.
AIM To evaluate the role of probiotics in the standard triple Helicobacter pylori therapy. METHODS In this meta-analysis, we investigated the efficacy of probiotics in a standard triple H. pylori
Lactobacillus-containing probiotic supplementation increases Helicobacter pylori eradication rate: evidence from a meta-analysis.
  • Xi Zheng, Lin Lyu, Z. Mei
  • Medicine
    Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva
  • 2013
Lactobacillus-containing probiotic as an adjunct is effective to eradication therapy, while side effects caused by eradication treatment may not decrease.
A Lyophilized Form of Saccharomyces Boulardii Enhances the Helicobacter pylori Eradication Rates of Omeprazole-Triple Therapy in Patients With Peptic Ulcer Disease or Functional Dyspepsia
S. boulardii enhanced the effect of classic triple therapy mainly by preventing antibiotic- and/or proton pump inhibitor-induced diarrhea.