Systematic review with meta‐analysis: Saccharomyces boulardii supplementation and eradication of Helicobacter pylori infection

@article{Szajewska2015SystematicRW,
  title={Systematic review with meta‐analysis: Saccharomyces boulardii supplementation and eradication of Helicobacter pylori infection},
  author={Hania Szajewska and Andrea Horv{\'a}th and Maciej Kołodziej},
  journal={Alimentary Pharmacology \& Therapeutics},
  year={2015},
  volume={41}
}
Unsatisfactory Helicobacter pylori eradication rates and therapy‐associated side effects remain a problem. 
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References

SHOWING 1-10 OF 45 REFERENCES
Meta‐analysis: the effects of Saccharomyces boulardii supplementation on Helicobacter pylori eradication rates and side effects during treatment
Aliment Pharmacol Ther 2010; 32: 1069–1079
A randomized, open trial evaluating the effect of Saccharomyces boulardii on the eradication rate of Helicobacter pylori infection in children
TLDR
The failure rate of Helicobacter pylori eradication imposes the assessment of new options in eradication and this results in the development of new strategies for eradication of the bug.
Meta‐analysis: non‐pathogenic yeast Saccharomyces boulardii in the prevention of antibiotic‐associated diarrhoea
TLDR
This work has shown that probiotic‐associated diarrhoea occurs in up to 30% of patients who receive antibiotics but can be prevented with probiotics, and this should not be considered a cause for concern.
Optimised empiric triple and concomitant therapy for Helicobacter pylori eradication in clinical practice: the OPTRICON study
TLDR
Empiric triple therapy for Helicobacter pylori should be abandoned when clarithromycin resistance rate is >15–20%, and optimisation of triple therapy can increase eradication rates by 10%.
The Effect of Probiotics and Mucoprotective Agents on PPI‐Based Triple Therapy for Eradication of Helicobacter pylori
TLDR
This work evaluated the additive effects of Saccharomyces boulardii combined with proton pump inhibitor (PPI)‐based triple therapy and a mucoprotective agent coupled with PPI‐ based triple therapy for HP eradication.
Efficacy and Safety of Saccharomyces boulardii in the 14‐day Triple Anti‐Helicobacter pylori Therapy: A Prospective Randomized Placebo‐Controlled Double‐Blind Study
TLDR
The aim of the study was to investigate the efficacy and safety of S. boulardii in the prevention of side‐effects related to H. pylori eradication and to define the effect ofS.
Intervention study on Saccharomyces boulardii with proton pump inhibitor (PPI)-based triple therapy for Helicobacter pylori related peptic ulcer
TLDR
S. boulardii with PPI-based triple therapy for peptic ulcer is effective with a low recurrence rate and can reduce the incidence of adverse events.
Meta-analysis of the efficacy of probiotics in Helicobacter pylori eradication therapy.
AIM To evaluate the role of probiotics in the standard triple Helicobacter pylori therapy. METHODS In this meta-analysis, we investigated the efficacy of probiotics in a standard triple H. pylori
Lactobacillus-containing probiotic supplementation increases Helicobacter pylori eradication rate: evidence from a meta-analysis.
  • Xi Zheng, Lin Lyu, Z. Mei
  • Medicine
    Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva
  • 2013
TLDR
Lactobacillus-containing probiotic as an adjunct is effective to eradication therapy, while side effects caused by eradication treatment may not decrease.
A Lyophilized Form of Saccharomyces Boulardii Enhances the Helicobacter pylori Eradication Rates of Omeprazole-Triple Therapy in Patients With Peptic Ulcer Disease or Functional Dyspepsia
TLDR
S. boulardii enhanced the effect of classic triple therapy mainly by preventing antibiotic- and/or proton pump inhibitor-induced diarrhea.
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