Systematic review on the efficacy, safety, and cost-effectiveness of topical calcineurin inhibitors in atopic dermatitis.

BACKGROUND Topical calcineurin inhibitors (TCIs) are widely used as an alternative to topical corticosteroids (TCSs) in treating of atopic dermatitis, but their risk versus benefit compared with TCSs remains unclear. OBJECTIVE We performed a systematic review of the efficacy, safety, and cost-effectiveness of TCI compared with TCS and emollients… CONTINUE READING