• Corpus ID: 44827725

Systematic review of the non-specific effects of BCG , DTP and measles containing vaccines

  title={Systematic review of the non-specific effects of BCG , DTP and measles containing vaccines},

Analysis of risk factors for infant mortality in the 1992-3 and 2002-3 birth cohorts in rural Guinea-Bissau

Due to beneficial non-specific effects for girls, the increased coverage of measles vaccination may have contributed to the disproportional decline in mortality by sex and age group.

Evidence of Increase in Mortality After the Introduction of Diphtheria–Tetanus–Pertussis Vaccine to Children Aged 6–35 Months in Guinea-Bissau: A Time for Reflection?

Although having better nutritional status and being protected against three infections, 6–35 months old DTP-vaccinated children tended to have higher mortality than D TP-un vaccinated children.

Cost-effectiveness of providing measles vaccination to all children in Guinea-Bissau

Taking the low cost of MV and the beneficial non-specific effects of MV into consideration, a 10-dose MV vial should be reclassified as a ‘1+ dose vial’.

Sex-differential heterologous (non-specific) effects of vaccines: an emerging public health issue that needs to be understood and exploited

This review discusses the evidence, mechanisms and public health implications of the non-specific effects of vaccines (NSEs), including sex-differential effects, and describes how advances in systems biology might be applied to study such effects.

Randomized Trials Comparing Inactivated Vaccine After Medium- or High-titer Measles Vaccine With Standard Titer Measles Vaccine After Inactivated Vaccine: A Meta-analysis.

Mortality in girls was higher when they had received inactivated vaccines (after MTMV or HTMV) rather than live standard titer MV (after an inactivated vaccine) after 9 months of age.

The WHO Review of the Possible Nonspecific Effects of Diphtheria-Tetanus-Pertussis Vaccine

Bias does not seem to explain why DTP is associated with higher mortality, and the observed inconsistencies in results were because of methodologic differences between studies.

Randomized Trials Comparing Inactivated Vaccine After Medium or High Titer Measles Vaccine with Standard Titer Measles Vaccine After Inactivated Vaccine: A Meta-Analysis.

After 9 months of age, all children had been immunized against measles, and mortality in girls was higher when they had received inactivated vaccines (after medium or high titer MV) rather than live standard titer VM (after an inactivated vaccine).



Sex Differential Effects of Routine Immunizations and Childhood Survival in Rural Malawi

The female–male mortality ratio varied with age, and BCG, DTP1 and MV had differential effects for girls and boys like in previous studies from West Africa.

Childhood mortality among users and non-users of primary health care in a rural west African community.

It is concluded that VHWs contribute to a better survival of young children through regular personal contact with the household through regular Personal Contact with the Household.

Evaluation of non‐specific effects of infant immunizations on early infant mortality in a southern Indian population

Objective  The aim of this study was to assess the relationship between receipt of routine childhood immunizations and infant mortality before 6 months of age.

Routine vaccinations and child survival: follow up study in Guinea-Bissau, West Africa.

Measles and BCG vaccines may have beneficial effects in addition to protection against measles and tuberculosis, and are unlikely to be explained exclusively by selection biases since different vaccines were associated with opposite tendencies.

Non‐specific sex‐differential effect of DTP vaccination may partially explain the excess girl child mortality in Ballabgarh, India

To test the hypothesis that a gender differential exists in the effect on child mortality of BCG, DTP, measles vaccine as administered under programme conditions in Ballabgarh HDSS area, a large number of children in the area have received the measles vaccine.

Benefits of routine immunizations on childhood survival in Tari, Southern Highlands Province, Papua New Guinea.

Routine immunizations are effective in reducing overall mortality in young children in an area of high mortality, in contrast to findings reported from Guinea-Bissau.

Non‐specific effects of diphtheria‐tetanus‐pertussis and measles vaccinations? An analysis of surveillance data from Navrongo, Ghana

Examining the impact of vaccinations on child mortality in Navrongo, Ghana found measles vaccine is associated with lower mortality and diphtheria‐tetanus‐pertussis with relatively higher mortality.

The introduction of diphtheria-tetanus-pertussis vaccine and child mortality in rural Guinea-Bissau: an observational study.

In low-income countries with high mortality, DTP as the last vaccine received may be associated with slightly increased mortality, and the role of DTP in high mortality areas needs to be clarified.