Systematic review of the definition and measurement of anastomotic leak after gastrointestinal surgery

  title={Systematic review of the definition and measurement of anastomotic leak after gastrointestinal surgery},
  author={Julie Bruce and Zygmunt H. Krukowski and G Al-Khairy and E M Russell and K. G. M. Park},
  journal={British Journal of Surgery},
Anastomotic leak after gastrointestinal surgery is an important postoperative event that leads to significant morbidity and mortality. Postoperative leak rates are frequently used as an indicator of the quality of surgical care provided. Comparison of rates between and within institutions depends on the use of standard definitions and methods of measurement of anastomotic leak. The aim of this study was to review the definition and measurement of anastomotic leak after oesophagogastric… 

Systematic review of methods to predict and detect anastomotic leakage in colorectal surgery

The purpose of this paper is to review current developments in the field and to identify strategies for early detection and treatment of anastomotic leakage.

Estimated Rate of Post-Operative Anastomotic Leak Following Colorectal Resection Surgery: A Systematic Review

A systematic review of the literature to assess the incidence of post-operative leak and identify patient factors associated with the development of leaks found that hospitalization and healthcare costs following colorectal resection surgery are increased.

Management of anastomotic leakage after rectal surgery: a review article.

Anastomotic leaks (ALs) are associated with increased perioperative morbidity and mortality, prolonged length of stay, higher readmission rates, the potential need for further operative

The management and outcome of anastomotic leaks in colorectal surgery

The aim of this study was to look at the diagnosis, clinical management and outcomes of anastamotic leaks in the department.

Intraoperative and postoperative diagnosis of anastomotic leak following colorectal resection

The focus of this article is to identify strategies to detect anastomotic leak using both intraoperative and postoperative criteria.

Intra-Operative Anastomotic Leak Rates and Testing Methodology in Colorectal Resection Surgery

A systematic review of the literature estimated the rate of intra-operative anastomotic leaks in colorectal resection surgery with high rates of morbidity, infection, and escalated healthcare expenditures.

Systematic review of preoperative, intraoperative and postoperative risk factors for colorectal anastomotic leaks

A systematic review of the literature focusing on the role of preoperative, intraoperative and postoperative factors in the development of colorectal ALs found that there remains a lack of consensus regarding factors that may predispose to AL.

Emerging Trends in the Etiology, Prevention, and Treatment of Gastrointestinal Anastomotic Leakage

The International Multispecialty Anastomotic Leak Global Improvement Exchange group was convened to establish a consensus on the definition of an anastomosis as well as to discuss the various diagnostic, preventative, and management measures currently available.

[Anastomotic leaks in the upper gastrointestinal tract].

The spectrum of therapeutic options ranges from simple opening of the neck incision in cervical esophageal anastomoses, interventional placement of drains, to endoscopic intervention with closure of the fistula or placement of stents, and reoperation with exclusion, diversion, or discontinuity resection.

Anastomotic leakage after esophagectomy for esophageal cancer: definitions, diagnostics, and treatment

The purpose of this review is to provide a cutting edge overview of the recent literature regarding the definition and classification of anastomotic leakage, risk factors, novel diagnostic modalities, and emerging therapeutic options for treatment and prevention of anamotic leakage following esophagectomy.



Role of gastrografin study in the assessment of anastomotic leaks from cervical oesophagogastric anastomosis.

A contrast study may be unnecessary for evaluation of a cervical oesophagogastric anastomosis and can be replaced with the simpler and safer technique of 'test feeding' using water.

Influence of a defunctioning stoma on leakage rates after low colorectal anastomosis and colonic J pouch–anal anastomosis

Anal sphincter function is increasingly preserved following rectal excision for cancer and provides a better quality of life for patients than does a permanent colostomy, and the incidence of anastomotic complications following two forms of reconstruction after resection for mid‐rectal cancer is examined.

Intraoperative colonic lavage and primary anastomosis in peritonitis and obstruction

The aim of this study was to evaluate the differences in outcome in patients with peritonitis or obstruction treated by resection, on‐table lavage and primary anastomosis of the left colon.

A randomised study of colostomies in low colorectal anastomoses.

The results suggest that a covering colostomy does not reduce the leak rate after low anterior resection, but prevents most of the severe infective consequences of the leaks.

Single-layer continuous anastomosis in gastrointestinal surgery: a prospective audit.

These results show that the single-layer continuous suture technique is safe in gastrointestinal anastomoses.

Anastomotic leakage: impact on local recurrence and survival in surgery of colorectal cancer

Anastomotic leakage appears to be a prognostic factor for local tumor recurrence of colorectal cancer in patients treated with adenocarcinoma of the left colon and rectum between 1985 and 1995.

Randomized trial of pelvic drainage after rectal resection

Use of a pelvic drain after rectal resection did not confer any benefit to the patient and Pelvic fluid collections were more likely to be demonstrated if a drain was used; however, this did not reach statistical significance.

Morbidity and mortality after single- and double-stapled colorectal anastomoses in patients with carcinoma of the rectum.

The results suggest that the double-stapling technique is as safe as the single-stapled technique for constructing an anastomosis after excision of the rectum for cancer, in terms of the risk of leakage, the development of an anastsomotic stricture, or local recurrence.

Omentoplasty in the prevention of anastomotic leakage after colonic or rectal resection: a prospective randomized study in 712 patients. French Associations for Surgical Research.

Investigation of the role of omentoplasty in the prevention of anastomotic leakage after colonic or rectal resection found it decreases neither the rate nor the severity of anASTomotic failure.