Systematic review of microsatellite instability and colorectal cancer prognosis.

@article{Popat2005SystematicRO,
  title={Systematic review of microsatellite instability and colorectal cancer prognosis.},
  author={Sanjay Popat and Ricardo Arthur Hubner and Richard S. Houlston},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2005},
  volume={23 3},
  pages={609-18}
}
PURPOSE A number of studies have investigated the relationship between microsatellite instability (MSI) and colorectal cancer (CRC) prognosis. Although many have reported a better survival with MSI, estimates of the hazard ratio (HR) among studies differ. To derive a more precise estimate of the prognostic significance of MSI, we have reviewed and pooled data from published studies. METHODS Studies stratifying survival in CRC patients by MSI status were eligible for analysis. The principal… CONTINUE READING
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