Systematic review of intestinal microbiota transplantation (fecal bacteriotherapy) for recurrent Clostridium difficile infection.

@article{Gough2011SystematicRO,
  title={Systematic review of intestinal microbiota transplantation (fecal bacteriotherapy) for recurrent Clostridium difficile infection.},
  author={Ethan K. Gough and Henna Shaikh and Amee R. Manges},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2011},
  volume={53 10},
  pages={
          994-1002
        }
}
Clostridium difficile infection (CDI) is a gastrointestinal disease believed to be causally related to perturbations to the intestinal microbiota. When standard treatment has failed, intestinal microbiota transplantation (IMT) is an alternative therapy for patients with CDI. IMT involves infusing intestinal microorganisms (in a suspension of healthy donor stool) into the intestine of a sick patient to restore the microbiota. However, protocols and reported efficacy for IMT vary. We conducted a… Expand

Paper Mentions

Interventional Clinical Trial
Constipation is the most common complaint in childhood gastrointestinal disease, affecting an estimated 20% of the global children.The treatment strategies consist of diet control… Expand
ConditionsConstipation - Functional, Fecal Microbiota Transplantation
InterventionDrug
Interventional Clinical Trial
The purpose of the study is to determine the safety and efficacy of Fecal Microbiota Transplant (FMT) for the treatment of the recurrence of Clostridium difficile infection (CDI… Expand
ConditionsClostridium Difficile Infection
InterventionBiological, Drug
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This is the first prospective, multi-center, double-blinded, randomized controlled study of a microbiota suspension derived from intestinal microbes. Patients who have had at least two… Expand
ConditionsEnterocolitis Clostridium Difficile Recurrent
InterventionBiological, Other
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