Systematic review of green tea epigallocatechin gallate in reducing low-density lipoprotein cholesterol levels of humans

@article{Momose2016SystematicRO,
  title={Systematic review of green tea epigallocatechin gallate in reducing low-density lipoprotein cholesterol levels of humans},
  author={Yuko Momose and Mari Maeda-Yamamoto and Hiroshi Nabetani},
  journal={International Journal of Food Sciences and Nutrition},
  year={2016},
  volume={67},
  pages={606 - 613}
}
Abstract We conducted a systematic review of the literature for the ability of green tea epigallocatechin gallate (EGCG) to lower low-density lipoprotein cholesterol (LDL-C). Study subjects were limited to healthy individuals and randomized, controlled trials on human serum lipid levels, especially LDL-C, conducted. A total of 17 trials (n = 1356) met all of the inclusion criteria. According to weighted mean differences for changes from baseline with 95% confidence intervals (CI), 107–856 mg/d… Expand
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References

SHOWING 1-10 OF 38 REFERENCES
Green tea catechins decrease total and low-density lipoprotein cholesterol: a systematic review and meta-analysis.
TLDR
The consumption of GTCs is associated with a statistically significant reduction in total and LDL cholesterol levels; however, there was no significant effect on HDL cholesterol or triglyceride levels. Expand
Green tea catechins and blood pressure: a systematic review and meta-analysis of randomised controlled trials
TLDR
The present meta-analysis suggests that green tea and its catechins may improve blood pressure, and the effect may be greater in those with systolic blood pressure ≥130 mm Hg. Expand
Ingestion of a tea rich in catechins leads to a reduction in body fat and malondialdehyde-modified LDL in men.
TLDR
Daily consumption of tea containing 690 mg catechins for 12 wk reduced body fat, which suggests that the ingestion of catechin might be useful in the prevention and improvement of lifestyle-related diseases, mainly obesity. Expand
Green tea intake lowers fasting serum total and LDL cholesterol in adults: a meta-analysis of 14 randomized controlled trials.
TLDR
The analysis of eligible studies showed that the administration of green tea beverages or extracts resulted in significant reductions in serum TC and LDL-cholesterol concentrations, but no effect on HDL cholesterol was observed. Expand
Therapeutic effect of high-dose green tea extract on weight reduction: A randomized, double-blind, placebo-controlled clinical trial.
TLDR
12 weeks of treatment with high-dose green tea extract resulted in significant weight loss, reduced waist circumference, and a consistent decrease in total cholesterol and LDL plasma levels without any side effects or adverse effects in women with central obesity. Expand
Consumption of green or black tea does not increase resistance of low-density lipoprotein to oxidation in humans.
TLDR
It is concluded that daily consumption of 900 mL (6 cups) green or black tea/d for 4 wk had no effect on serum lipid concentrations or resistance of LDL to oxidation ex vivo, although consumption of green tea slightly increased total antioxidant activity of plasma. Expand
Effectiveness of moderate green tea consumption on antioxidative status and plasma lipid profile in humans.
TLDR
The present study suggests the ability of GT, consumed within a balanced controlled diet, to improve overall the antioxidative status and to protect against oxidative damage in humans. Expand
Health effects of green tea catechins in overweight and obese men: a randomised controlled cross-over trial
TLDR
Body weight decreased and increased in the DGT and placebo groups, suggesting a protective effect of green tea catechins on weight gain, and the COMT Val/Met genotype influenced urinary accumulation of EGC and 4′-O-methyl EGC. Expand
Effects of Green Tea Supplementation on Elements, Total Antioxidants, Lipids, and Glucose Values in the Serum of Obese Patients
TLDR
It is demonstrated that green tea influences the body's mineral status and the beneficial effects of green tea extract supplementation on body mass index, lipid profile, and total antioxidant status in patients with obesity are confirmed. Expand
Tea Catechins Reduce Serum Cholesterol Levels in Mild and Borderline Hypercholesterolemia Patients
TLDR
The results demonstrated the benefits and safety of tea catechins in individuals with mild or borderline hypercholesterolemia and no abnormal findings were noted in blood tests, physical measurements and interviews by physicians. Expand
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