Systematic review and meta-analysis of rates of clozapine-associated myocarditis and cardiomyopathy

@article{Siskind2020SystematicRA,
  title={Systematic review and meta-analysis of rates of clozapine-associated myocarditis and cardiomyopathy},
  author={Dan J. Siskind and Ashneet Sidhu and John Cross and Yee-Tat Chua and Nicholas Myles and Dan Cohen and Stephen R Kisely},
  journal={Australian \& New Zealand Journal of Psychiatry},
  year={2020},
  volume={54},
  pages={467 - 481}
}
Background: Clozapine is the most effective medication for treatment refractory schizophrenia, but is associated with cardiac adverse drug reactions. Myocarditis and cardiomyopathy are the most serious cardiac adverse drug reactions although reported rates of these conditions vary in the literature. We systematically reviewed and meta-analysed the event rates, the absolute death rates and case fatality rates of myocarditis and cardiomyopathy associated with clozapine. Methods: PubMed, EMBASE… 

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