Systematic review and meta-analysis of randomized controlled trials comparing botulinum toxin injection with lateral internal sphincterotomy for chronic anal fissure

@article{Shao2009SystematicRA,
  title={Systematic review and meta-analysis of randomized controlled trials comparing botulinum toxin injection with lateral internal sphincterotomy for chronic anal fissure},
  author={W. Shao and Guo-Chun Li and Zhikun Zhang},
  journal={International Journal of Colorectal Disease},
  year={2009},
  volume={24},
  pages={995-1000}
}
ObjectiveThe aim of this review is to systematically analyze the prospective randomized controlled trials on the efficacy of botulinum toxin injection (Botox) vs. lateral internal sphincterotomy (LIS) for the treatment of chronic anal fissure (CAF).Materials and methodsA systematic review of the literature was undertaken. The prospective randomized controlled trials on the effectiveness of Botox vs. LIS for the management of CAF were selected according to specific criteria and analyzed to… Expand
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