Systematic review and meta-analysis of radiotherapy in various head and neck cancers: comparing photons, carbon-ions and protons.

@article{Ramaekers2011SystematicRA,
  title={Systematic review and meta-analysis of radiotherapy in various head and neck cancers: comparing photons, carbon-ions and protons.},
  author={Bram L T Ramaekers and Madelon C G Pijls-Johannesma and Manuela M A Joore and Piet L A van den Ende and Johannes A. Langendijk and Philippe Lambin and Alphons G. H. Kessels and Janneke P C Grutters},
  journal={Cancer treatment reviews},
  year={2011},
  volume={37 3},
  pages={
          185-201
        }
}
PURPOSE To synthesize and compare available evidence considering the effectiveness of carbon-ion, proton and photon radiotherapy for head and neck cancer. METHODS A systematic review and meta-analyses were performed to retrieve evidence on tumor control, survival and late treatment toxicity for carbon-ion, proton and the best available photon radiotherapy. RESULTS In total 86 observational studies (74 photon, 5 carbon-ion and 7 proton) and eight comparative in-silico studies were included… CONTINUE READING
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