Systematic review: maintenance treatment of gastro-oesophageal reflux disease with proton pump inhibitors taken 'on-demand'.

@article{Pace2007SystematicRM,
  title={Systematic review: maintenance treatment of gastro-oesophageal reflux disease with proton pump inhibitors taken 'on-demand'.},
  author={F{\'a}bio Pace and Marcello Tonini and Stefano Pallotta and Paola Molteni and Gabriele Bianchi Porro},
  journal={Alimentary pharmacology & therapeutics},
  year={2007},
  volume={26 2},
  pages={
          195-204
        }
}
  • Fábio Pace, Marcello Tonini, +2 authors Gabriele Bianchi Porro
  • Published in
    Alimentary pharmacology…
    2007
  • Medicine
  • BACKGROUND Proton pump inhibitors (PPI) therapy 'on-demand' is often used as an alternative to continuous maintenance therapy in gastro-oesophageal reflux disease (GERD). AIM We conducted a systematic review with the specific objectives to ascertain whether on-demand PPI therapy was effective in preventing symptomatic relapse and to assess the relative efficacy of on-demand vs. continuous PPI maintenance strategy. METHODS Randomized-controlled clinical trials comparing on-demand PPI vs… CONTINUE READING

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