Systematic review: antibodies and anti-TNF-α levels in inflammatory bowel disease.

  title={Systematic review: antibodies and anti-TNF-α levels in inflammatory bowel disease.},
  author={Mar{\'i}a Chaparro and Iv{\'a}n Guerra and P Mu{\~n}oz-Linares and Javier P Gisbert},
  journal={Alimentary pharmacology & therapeutics},
  volume={35 9},
BACKGROUND The associations between clinical efficacy and infusion reactions with anti-TNF-α drug levels and the presence of antibodies against the drug have been described. However, the clinical utility of these tests in routine clinical practice remains unclear. AIMS To examine the clinical significance of the development of antibodies against anti-TNF-α drugs and the relationship between the efficacy of these drugs and their serum levels. We also studied the clinical utility of testing for… CONTINUE READING


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