Systematic investigation of insertional and deletional RNA-DNA differences in the human transcriptome

@inproceedings{Chen2012SystematicIO,
  title={Systematic investigation of insertional and deletional RNA-DNA differences in the human transcriptome},
  author={Cai Chen and Ralf Bundschuh},
  booktitle={BMC Genomics},
  year={2012}
}
The genomic information which is transcribed into the primary RNA can be altered by RNA editing at the transcriptional or post-transcriptional level, which provides an effective way to create transcript diversity in an organism. Altering can occur through substitutional RNA editing or via the insertion or deletion of nucleotides relative to the original template. Taking advantage of recent high throughput sequencing technology combined with bioinformatics tools, several groups have recently… CONTINUE READING
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